Carbamazepine has had some bad press lately due to the association of Stevens Johnson Syndrome and toxic epidermal necrolysis with the HLA allele HLA B*1502.
But this pharmaceutical has many excellent uses. One of the lesser known is for restless legs syndrome.
http://www.ncbi.nlm.nih.gov/pubmed/6419958?dopt=Abstract
In this placebo controlled study, carbamazepine was more effective than placebo at p <0.03, which is pretty good data for a study of that era. Reading between the lines, the patients who responded best probably would have had low ferritin levels.
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